Population dynamics of bovine herpesvirus 1 infection in a dairy herd

Vet Microbiol. 1996 Nov;53(1-2):169-80. doi: 10.1016/s0378-1135(96)01245-x.

Abstract

An induced outbreak of a bovine herpesvirus 1 (BHV1) infection in a dairy herd is described. The outbreak was induced by injecting three BHV1 seropositive cows with dexamethasone. Within 7 weeks all seronegative cows had seroconverted. Also some seropositive animals showed a significant increase in serum antibody titre. Using these data, parameters of population dynamics such as R0, the basic reproduction ratio, could be estimated. The basic reproduction ratio is a threshold value describing infection dynamics in a population. This parameter is defined as the average number of secondary cases generated by one primary case in a wholly susceptible population of defined density. In this population R0 was estimated to be at least 7. The importance of these findings, and implications for eradication of BHV1 are discussed.

MeSH terms

  • Animals
  • Cattle
  • Cattle Diseases*
  • Dexamethasone / adverse effects*
  • Disease Outbreaks / veterinary*
  • Female
  • Herpesviridae Infections / epidemiology
  • Herpesviridae Infections / etiology
  • Herpesviridae Infections / veterinary*
  • Herpesvirus 1, Bovine* / growth & development
  • Infectious Bovine Rhinotracheitis / epidemiology*
  • Infectious Bovine Rhinotracheitis / etiology
  • Lactation
  • Population Dynamics
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology
  • Pregnancy Complications, Infectious / veterinary*
  • Pregnancy Complications, Infectious / virology
  • Viral Vaccines
  • Virus Activation

Substances

  • Viral Vaccines
  • Dexamethasone