[Changes in the surface architectonics of erythrocytes under the influence of the synthetic antioxidant fenozan-1]

Izv Akad Nauk Ser Biol. 1996 Jul-Aug:(4):508-12.
[Article in Russian]

Abstract

Scanning electron microscopy revealed changes in erythrocyte morphology induced by the synthetic antioxidant phenozan-1. Phenozan-1 at 10(-7)-10(-5) M acts as an echinocytogen. This effect of the antioxidant is, probably, due to its distribution in the external monolayer of the erythrocyte membrane and associated structural changes.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Antioxidants / pharmacology*
  • Dose-Response Relationship, Drug
  • Erythrocyte Membrane / drug effects*
  • Erythrocyte Membrane / ultrastructure
  • Humans
  • Microscopy, Electron, Scanning
  • Phenylpropionates / pharmacology*
  • Surface Properties

Substances

  • Antioxidants
  • Phenylpropionates
  • fenozan