Serological profiles of hepatitis B carrier patients in Singapore with special reference to the frequency and significance of concurrent presence of HBsAg and anti-HBs

Y M Wang; W C Ng; J Y Kang; I Yap; B L Seet; J Teo; R Smith; R Guan

Serological profiles of hepatitis B carrier patients in Singapore with special reference to the frequency and significance of concurrent presence of HBsAg and anti-HBs

Singapore Med J. 1996 Apr;37(2):150-2.

Authors

Y M Wang¹, W C Ng, J Y Kang, I Yap, B L Seet, J Teo, R Smith, R Guan

Affiliation

¹ Department of Medicine National University of Singapore, Singapore.

PMID: 8942251

Abstract

Hepatitis B serological markers were investigated in 1,132 consecutive Singaporean HBV carriers. Hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) were found concurrently in 234 carriers (234/1132 or 21%). Serum anti-HBs levels were more than 10 mIU/mL in 80 of these carriers (80/234 or 34%). There were no difference in HBeAg positive status, as well as HBV-DNA positive status in concurrent HBsAg/anti-HBs carriers compared to carriers without anti-HBs. Our results suggested that concurrent HBsAg and anti-HBs is a common serologic pattern in Singaporean HBV carriers.

MeSH terms

Adolescent
Adult
Age Factors
Aged
Carrier State / epidemiology
Carrier State / immunology*
Child
Female
Hepatitis B / epidemiology
Hepatitis B / immunology*
Hepatitis B Antibodies / analysis*
Hepatitis B Surface Antigens / analysis*
Humans
Incidence
Male
Middle Aged
Sensitivity and Specificity
Serologic Tests
Singapore

Substances

Hepatitis B Antibodies
Hepatitis B Surface Antigens