Cell-cell signalling: Wingless lands at last

Curr Biol. 1996 Nov 1;6(11):1363-7. doi: 10.1016/s0960-9822(96)00731-2.

Abstract

A novel class of receptor-the Frizzled family-has been identified and the members shown to be receptors for Wingless and its homologs, the Wnts, which mediate key cell-cell interactions during the development of fruitflies and vertebrates, respectively.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Communication
  • Drosophila / metabolism*
  • Drosophila Proteins*
  • Frizzled Receptors
  • Hedgehog Proteins
  • Humans
  • Insect Proteins / metabolism
  • Proto-Oncogene Proteins / metabolism*
  • Receptors, Cell Surface / metabolism*
  • Receptors, G-Protein-Coupled
  • Receptors, Neurotransmitter*
  • Signal Transduction / physiology*
  • Wnt1 Protein

Substances

  • Drosophila Proteins
  • Frizzled Receptors
  • Hedgehog Proteins
  • Insect Proteins
  • Proto-Oncogene Proteins
  • Receptors, Cell Surface
  • Receptors, G-Protein-Coupled
  • Receptors, Neurotransmitter
  • Wnt1 Protein
  • fz2 protein, Drosophila
  • wg protein, Drosophila
  • hh protein, Drosophila