Abstract
A novel class of receptor-the Frizzled family-has been identified and the members shown to be receptors for Wingless and its homologs, the Wnts, which mediate key cell-cell interactions during the development of fruitflies and vertebrates, respectively.
Publication types
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Research Support, U.S. Gov't, P.H.S.
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Review
MeSH terms
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Animals
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Cell Communication
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Drosophila / metabolism*
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Drosophila Proteins*
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Frizzled Receptors
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Hedgehog Proteins
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Humans
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Insect Proteins / metabolism
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Proto-Oncogene Proteins / metabolism*
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Receptors, Cell Surface / metabolism*
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Receptors, G-Protein-Coupled
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Receptors, Neurotransmitter*
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Signal Transduction / physiology*
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Wnt1 Protein
Substances
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Drosophila Proteins
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Frizzled Receptors
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Hedgehog Proteins
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Insect Proteins
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Proto-Oncogene Proteins
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Receptors, Cell Surface
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Receptors, G-Protein-Coupled
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Receptors, Neurotransmitter
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Wnt1 Protein
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fz2 protein, Drosophila
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wg protein, Drosophila
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hh protein, Drosophila