[Cervical metastasis of squamous cell carcinoma of unknown origin: experience at Hospital de Sant Pau, Barcelona, Spain]

Acta Otorrinolaringol Esp. 1996 May-Jun;47(3):233-8.
[Article in Spanish]

Abstract

Between 1984 and 1992, 18 cases of cervical metastasis of squamous cell or anaplastic carcinoma (1% of all head and neck tumors) were seen at the Hospital de la Santa Creu i Sant Pau (Barcelona, Spain). Fifteen patients underwent radical surgery: 1 N1, 4 N2A and 10N3, N1 and N2A patients underwent surgery followed by radiotherapy. The 10 N3 patients began with neoadjuvant chemotherapy (cisplatin and 5-fluorouracil), then 8 had radical neck dissection and 2 had palliative radiotherapy. The primary tumor was found in 11%. The 5-year survival rate was 40% in N1+2A and 11% in N3. Chemotherapy did not improve survival in advanced disease, but it facilitated neck dissection and selection of the group with the prognosis.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Agents / therapeutic use
  • Carcinoma, Squamous Cell / drug therapy
  • Carcinoma, Squamous Cell / epidemiology*
  • Carcinoma, Squamous Cell / surgery
  • Cervical Vertebrae / pathology*
  • Cisplatin / therapeutic use
  • Female
  • Fluorouracil / therapeutic use
  • Head and Neck Neoplasms / drug therapy
  • Head and Neck Neoplasms / epidemiology*
  • Head and Neck Neoplasms / surgery
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Radiotherapy
  • Sex Factors
  • Spain / epidemiology

Substances

  • Antineoplastic Agents
  • Cisplatin
  • Fluorouracil