Increased QT dispersion and cardiac adrenergic dysinnervation in diabetic patients with autonomic neuropathy

M Shimabukuro; T Chibana; H Yoshida; F Nagamine; I Komiya; N Takasu

doi:10.1016/s0002-9149(96)00538-3

Increased QT dispersion and cardiac adrenergic dysinnervation in diabetic patients with autonomic neuropathy

Am J Cardiol. 1996 Nov 1;78(9):1057-9. doi: 10.1016/s0002-9149(96)00538-3.

Authors

M Shimabukuro¹, T Chibana, H Yoshida, F Nagamine, I Komiya, N Takasu

Affiliation

¹ Second Department of Internal Medicine Faculty of Medicine, University of The Ryukyus, Nishihara, Okinawa, Japan.

PMID: 8916492
DOI: 10.1016/s0002-9149(96)00538-3

Abstract

Diabetic patients with autonomic neuropathy showed an increase in QTc dispersion correlated with cardiac adrenergic dysinnervation. A larger prospective study in a diabetic population is needed to assess whether QT dispersion increases the risk of arrhythmogenicity through autonomic dysfunction.

MeSH terms

Adrenergic Fibers*
Aged
Case-Control Studies
Diabetes Mellitus, Type 2 / complications
Diabetes Mellitus, Type 2 / physiopathology*
Diabetic Neuropathies / diagnostic imaging
Diabetic Neuropathies / etiology
Diabetic Neuropathies / physiopathology*
Electrocardiography
Female
Heart / diagnostic imaging
Heart / innervation*
Heart / physiopathology*
Humans
Male
Middle Aged
Tomography, Emission-Computed, Single-Photon