Chemical mechanisms of formation of DNA-carcinogen adducts, elucidation of potential of adducts for mutagenicity, and mechanisms of polymerase fidelity and mutation in the presence of adducts

Recent Results Cancer Res. 1997:143:49-63. doi: 10.1007/978-3-642-60393-8_4.
No abstract available

Publication types

  • Review

MeSH terms

  • Aflatoxin B1 / toxicity
  • Animals
  • Base Sequence
  • Carcinogens*
  • Cell Transformation, Neoplastic*
  • DNA Adducts*
  • DNA Polymerase II / metabolism
  • DNA-Directed DNA Polymerase / metabolism*
  • Escherichia coli / enzymology
  • Escherichia coli / genetics
  • Humans
  • Kinetics
  • Models, Biological
  • Mutagenesis*
  • Substrate Specificity

Substances

  • Carcinogens
  • DNA Adducts
  • Aflatoxin B1
  • DNA Polymerase II
  • DNA-Directed DNA Polymerase