A null allele for the Afm175xg3 marker at locus D17S795 caused by a primer binding failure

Int J Legal Med. 1996;109(2):104-6. doi: 10.1007/BF01355528.

Abstract

We found a null allele for the marker Afm175xg3, at locus D17S795, due to primer binding failure, which makes this polymorphic marker unsuitable for genetic and forensic studies. This problem can be overcome by designing two new primers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Binding Sites / genetics*
  • Chromosomes, Human, Pair 17 / genetics
  • DNA Fingerprinting*
  • DNA Primers / genetics
  • Genetic Carrier Screening / methods*
  • Genotype
  • Humans
  • Microsatellite Repeats / genetics*
  • Pedigree
  • Polymerase Chain Reaction / methods
  • Polymorphism, Genetic / genetics*

Substances

  • DNA Primers