Unusual chromosome aberration, t(13;14)(q32;q32.3), in a case of essential thrombocythemia with extreme thrombocytosis

Cancer Genet Cytogenet. 1996 Oct 1;91(1):68-70. doi: 10.1016/s0165-4608(96)00153-7.

Abstract

A case of essential thrombocythemia (ET) with extreme thrombocytosis in a 70-year-old male patient is described. The cytogenetic analysis revealed a pathologic clone with the following previously unreported, unusual karyotype: 46,XY,t(13;14)(q32:q32.3) and pericentric inversion of chromosome 9. The possible association of t(13;14) with the high platelet count is discussed.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Chromosome Aberrations / genetics*
  • Chromosome Inversion*
  • Chromosomes, Human, Pair 13 / genetics*
  • Chromosomes, Human, Pair 14 / genetics*
  • Chromosomes, Human, Pair 9 / genetics*
  • Humans
  • Karyotyping
  • Male
  • Thrombocythemia, Essential / complications
  • Thrombocythemia, Essential / genetics*
  • Thrombocytosis / complications
  • Thrombocytosis / genetics*
  • Translocation, Genetic / genetics*