Abstract
A case of essential thrombocythemia (ET) with extreme thrombocytosis in a 70-year-old male patient is described. The cytogenetic analysis revealed a pathologic clone with the following previously unreported, unusual karyotype: 46,XY,t(13;14)(q32:q32.3) and pericentric inversion of chromosome 9. The possible association of t(13;14) with the high platelet count is discussed.
MeSH terms
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Aged
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Chromosome Aberrations / genetics*
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Chromosome Inversion*
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Chromosomes, Human, Pair 13 / genetics*
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Chromosomes, Human, Pair 14 / genetics*
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Chromosomes, Human, Pair 9 / genetics*
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Humans
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Karyotyping
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Male
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Thrombocythemia, Essential / complications
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Thrombocythemia, Essential / genetics*
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Thrombocytosis / complications
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Thrombocytosis / genetics*
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Translocation, Genetic / genetics*