Kynurenic acid-enhancing and anti-ischemic effects of the potent kynurenine 3-hydroxylase inhibitor FCE 28833 in rodents

Adv Exp Med Biol. 1996:398:221-7. doi: 10.1007/978-1-4613-0381-7_35.
No abstract available

MeSH terms

  • Animals
  • Brain / drug effects
  • Brain / metabolism*
  • Brain / pathology
  • Butyrates / pharmacology*
  • Enzyme Inhibitors / pharmacology*
  • Gerbillinae
  • Hippocampus / drug effects
  • Hippocampus / pathology
  • Hydrolases / metabolism
  • Ischemic Attack, Transient / pathology
  • Ischemic Attack, Transient / prevention & control*
  • Kynurenic Acid / metabolism*
  • Kynurenine 3-Monooxygenase
  • Liver / enzymology
  • Male
  • Mixed Function Oxygenases / antagonists & inhibitors*
  • Mixed Function Oxygenases / metabolism
  • Neurons / drug effects
  • Neurons / pathology
  • Neuroprotective Agents / pharmacology*
  • Rats
  • Rats, Wistar

Substances

  • Butyrates
  • Enzyme Inhibitors
  • FCE 28833
  • Neuroprotective Agents
  • Mixed Function Oxygenases
  • Kynurenine 3-Monooxygenase
  • Hydrolases
  • kynureninase
  • Kynurenic Acid