The structure of lactate dehydrogenase from Plasmodium falciparum reveals a new target for anti-malarial design

Nat Struct Biol. 1996 Nov;3(11):912-5. doi: 10.1038/nsb1196-912.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Antimalarials
  • Drug Design
  • Enzyme Inhibitors
  • L-Lactate Dehydrogenase / antagonists & inhibitors
  • L-Lactate Dehydrogenase / chemistry*
  • Models, Molecular
  • NAD / chemistry*
  • NAD / metabolism
  • Oxamic Acid / chemistry
  • Plasmodium falciparum / enzymology*
  • Protein Conformation*

Substances

  • Antimalarials
  • Enzyme Inhibitors
  • NAD
  • L-Lactate Dehydrogenase
  • Oxamic Acid