Successful treatment of lymphomatoid granulomatosis using cyclosporin-A after failure of intensive chemotherapy

Am J Hematol. 1996 Nov;53(3):192-5. doi: 10.1002/(SICI)1096-8652(199611)53:3<192::AID-AJH8>3.0.CO;2-U.

Abstract

We report the successful and maintained response of lymphomatoid granulomatosis using a new approach to therapy, cyclosporin-A, after failure of aggressive multiagent chemotherapy.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • CD4-Positive T-Lymphocytes / drug effects
  • CD4-Positive T-Lymphocytes / pathology
  • Combined Modality Therapy
  • Cyclophosphamide / administration & dosage
  • Cyclosporine / pharmacology
  • Cyclosporine / therapeutic use*
  • Doxorubicin / administration & dosage
  • Etoposide / administration & dosage
  • Humans
  • Immunosuppressive Agents / pharmacology
  • Immunosuppressive Agents / therapeutic use*
  • Lung Diseases / diagnosis
  • Lung Diseases / drug therapy
  • Lung Diseases / pathology
  • Lung Diseases / therapy*
  • Lymphomatoid Granulomatosis / diagnosis
  • Lymphomatoid Granulomatosis / drug therapy
  • Lymphomatoid Granulomatosis / pathology
  • Lymphomatoid Granulomatosis / therapy*
  • Male
  • Mechlorethamine / administration & dosage
  • Methotrexate / administration & dosage
  • Middle Aged
  • Prednisone / administration & dosage
  • Procarbazine / administration & dosage
  • Recurrence
  • Remission Induction
  • Salvage Therapy
  • Vincristine / administration & dosage

Substances

  • Immunosuppressive Agents
  • Procarbazine
  • Mechlorethamine
  • Vincristine
  • Etoposide
  • Doxorubicin
  • Cyclosporine
  • Cyclophosphamide
  • Prednisone
  • Methotrexate

Supplementary concepts

  • ProMACE-MOPP protocol