[Burned-out tumor and carcinoma-in-situ of the testis mimicking an extragonadal germ cell tumor: a case report]

Hinyokika Kiyo. 1996 Aug;42(8):613-6.
[Article in Japanese]

Abstract

Multiple tumors of mediastinum, retroperitoneum and lung were detected in a 40-year-old man presented with lumbago and lower abdominal pain. As biopsy specimen taken from the cervical lymph node suggested germ-cell tumor and his testes were normally palpable, the initial diagnosis was an extragonadal germ-cell tumor. However, since ultrasonography of his left testis showed a small high echoic lesion (5 mm) assumed to be a burned-out tumor, orchiectomy was performed. Histological findings confirmed scar tissue as burned-out tumor and also revealed some malignant cells lining the seminiferous tubules that were thought to be the carcinoma-in-situ of the testis. After chemotherapy of etoposide and cisplatinum he achieved a partial response which has been maintained for 7 months. Examinations for burned-out tumor or carcinoma-in-situ of the testis should be made for the patients with an extragonadal germ cell tumor who have normally palpable testes.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Carcinoma in Situ / diagnosis*
  • Carcinoma in Situ / therapy
  • Cisplatin / administration & dosage
  • Combined Modality Therapy
  • Diagnosis, Differential
  • Etoposide / administration & dosage
  • Germinoma / diagnosis*
  • Germinoma / therapy
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / therapy
  • Male
  • Mediastinal Neoplasms / diagnosis*
  • Mediastinal Neoplasms / therapy
  • Neoplasms, Multiple Primary*
  • Orchiectomy
  • Retroperitoneal Neoplasms / diagnosis*
  • Retroperitoneal Neoplasms / therapy
  • Testicular Neoplasms / diagnosis*
  • Testicular Neoplasms / therapy

Substances

  • Etoposide
  • Cisplatin