Prenatal biochemical diagnostics of inborn developmental defects

Sb Lek. 1994;95(4):277-83.

Abstract

Screening of pathological pregnancies with the use of biochemical markers determined in maternal serum is now widely accepted as a useful procedure. In our experience, the main contribution is a finding of abnormal values of one or more of the markers, which will advise gynecologist upon a possibility of a risk pregnancy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Biomarkers / blood*
  • Chorionic Gonadotropin / blood
  • Chromosomes, Human, Pair 18
  • Down Syndrome / blood
  • Down Syndrome / diagnosis
  • Female
  • Humans
  • Neural Tube Defects / blood
  • Neural Tube Defects / diagnosis
  • Pregnancy
  • Pregnancy-Specific beta 1-Glycoproteins / analysis
  • Prenatal Diagnosis*
  • Trisomy
  • alpha-Fetoproteins / analysis

Substances

  • Biomarkers
  • Chorionic Gonadotropin
  • Pregnancy-Specific beta 1-Glycoproteins
  • alpha-Fetoproteins