A measure of pupillary oscillation as a marker of cocaine-induced paranoia

R B Rosse; S K Johri; A L Hess; K Kendrick; T N Alim; S I Deutsch

doi:10.1176/jnp.8.3.347

A measure of pupillary oscillation as a marker of cocaine-induced paranoia

J Neuropsychiatry Clin Neurosci. 1996 Summer;8(3):347-50. doi: 10.1176/jnp.8.3.347.

Authors

R B Rosse¹, S K Johri, A L Hess, K Kendrick, T N Alim, S I Deutsch

Affiliation

¹ Department of Veterans Affairs Medical Center, Washington, D.C. 20422, USA.

PMID: 8854309
DOI: 10.1176/jnp.8.3.347

Abstract

Cocaine-induced paranoia (CIP) remains an important drug-induced model of idiopathic paranoia for which no psychophysiologic marker has yet emerged. Measures of pupillary oscillation were able to significantly distinguish a group of abstinent crack cocaine abusers endorsing past CIP (n = 32) from another group of crack addicts who denied past CIP (n = 29).

Publication types

Clinical Trial
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Adult
Crack Cocaine*
Female
Humans
Male
Narcotics*
Paranoid Disorders / chemically induced*
Paranoid Disorders / diagnosis
Pupil Disorders / chemically induced*
Reflex, Pupillary / drug effects
Reflex, Pupillary / physiology
Substance-Related Disorders / diagnosis*
Substance-Related Disorders / psychology*

Substances

Crack Cocaine
Narcotics