Poly(L-lactide) bone plates and screws for internal fixation of mandibular swing osteotomies

Int J Oral Maxillofac Surg. 1996 Feb;25(1):20-4. doi: 10.1016/s0901-5027(96)80006-3.

Abstract

This study evaluated bone healing after mandibular swing osteotomies fixed with biodegradable poly(L-lactide) (PLLA) bone plates in four patients. A step osteotomy treated with two PLLA bone plates (n=3), and a straight osteotomy treated with one PLLA bone plate (n=1) were performed. Bone healing was uneventful in all patients; only in the patient with the straight osteotomy was callus observed. After 5.5 years, radiologic changes at the site of implantation were observed in the remaining patient. Histologic examination revealed a nonspecific foreign-body reaction on highly crystalline PLLA remnants which were still present. It is concluded that the PLLA bone plates provided enough strength to enable undisturbed bone healing. The long-term degradation results are comparable with those of other studies on as-polymerized PLLA implants.

Publication types

  • Comparative Study

MeSH terms

  • Biodegradation, Environmental
  • Bone Plates*
  • Bone Screws*
  • Bony Callus / diagnostic imaging
  • Carcinoma, Squamous Cell / radiotherapy
  • Carcinoma, Squamous Cell / surgery
  • Crystallization
  • Equipment Design
  • Female
  • Follow-Up Studies
  • Foreign-Body Reaction / diagnostic imaging
  • Foreign-Body Reaction / pathology
  • Humans
  • Internal Fixators*
  • Male
  • Mandible / diagnostic imaging
  • Mandible / pathology
  • Mandible / surgery*
  • Middle Aged
  • Mouth Neoplasms / radiotherapy
  • Mouth Neoplasms / surgery
  • Oropharyngeal Neoplasms / radiotherapy
  • Oropharyngeal Neoplasms / surgery
  • Osteotomy / instrumentation*
  • Osteotomy / methods
  • Polyesters* / chemistry
  • Radiography
  • Wound Healing

Substances

  • Polyesters
  • poly(lactide)