Abstract
Forty-six isolates of Penicillium marneffei were differentiated into two DNA types on the basis of their restriction fragment length polymorphisms. Of the 22 human isolates of P. marneffei, 16 (72.7%) were type I and 6 (27.3%) were type II. Of the 23 bamboo rat isolates, 20 from Rhizomys sumatrensis were type I and 3 from Cannomys badius were type II. The soil isolate was type II. These data represent the first molecular epidemiological study of this important emerging fungal pathogen.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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AIDS-Related Opportunistic Infections / complications
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AIDS-Related Opportunistic Infections / microbiology
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Animals
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DNA, Fungal / genetics
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DNA, Fungal / isolation & purification
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Humans
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Molecular Epidemiology
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Muridae
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Mycoses / complications
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Mycoses / microbiology
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Penicillium / classification*
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Penicillium / genetics*
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Penicillium / isolation & purification
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Polymorphism, Restriction Fragment Length*
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Rats
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Soil Microbiology
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Species Specificity