Restriction endonuclease analysis of Penicillium marneffei

J Clin Microbiol. 1996 Jul;34(7):1834-6. doi: 10.1128/JCM.34.7.1834-1836.1996.

Abstract

Forty-six isolates of Penicillium marneffei were differentiated into two DNA types on the basis of their restriction fragment length polymorphisms. Of the 22 human isolates of P. marneffei, 16 (72.7%) were type I and 6 (27.3%) were type II. Of the 23 bamboo rat isolates, 20 from Rhizomys sumatrensis were type I and 3 from Cannomys badius were type II. The soil isolate was type II. These data represent the first molecular epidemiological study of this important emerging fungal pathogen.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • AIDS-Related Opportunistic Infections / complications
  • AIDS-Related Opportunistic Infections / microbiology
  • Animals
  • DNA, Fungal / genetics
  • DNA, Fungal / isolation & purification
  • Humans
  • Molecular Epidemiology
  • Muridae
  • Mycoses / complications
  • Mycoses / microbiology
  • Penicillium / classification*
  • Penicillium / genetics*
  • Penicillium / isolation & purification
  • Polymorphism, Restriction Fragment Length*
  • Rats
  • Soil Microbiology
  • Species Specificity

Substances

  • DNA, Fungal