Mobile cecum syndrome is characterized by chronic right lower quadrant pain with the evidence of neither appendicitis nor other pathological findings at operation. Two cases of mobile cecum syndrome are reported; both had intermittent right lower quadrant cramping pain for months. One had received appendectomy because of chronic right lower quadrant pain at another hospital about nine months before admission here. The symptoms did not improve postoperatively, and the patient underwent laparotomy under impression of partial intestinal obstruction. The other patient underwent laparotomy under impression of chronic appendicitis. At surgery, both were found to have cecum and ascending colon were not attached to the posterior parietal wall, and cecopexy was performed. They have now been symptom free for one year. Cecopexy appears therefore to be an effective method of treatment of mobile cecum syndrome.