Background: The exacerbation of porokeratosis of Mibelli associated with inmunosuppression has been well documented.
Materials and methods: We describe the clinical and histologic data of three cases of HIV-infected patients, who developed porokeratosis following HIV-contact.
Results: The three reported patients were found to have the clinical and histologic features of porokeratosis of Mibelli. Either the exacerbation or development of the disease followed HIV infection.
Conclusion: Although porokeratosis is not a disease indicative of AIDS, its flare-up or its presence in HIV-infected patients may serve as a marker of inmunodeficiency.