The extreme severity of hepatitis E in the pregnant patient results a high maternal and fetal mortality in fulminating acute hepatitis. We present a clinical case of a 19 years old primigesta, 29 weeks pregnant, diagnosted as suffering from Acute Fulminating Hepatitis non A non B, probably E. The fetus died and liver transplant was contemplated for the patient due to the severity of disease. Liver transplant could not be carried out for lack of a suitable donor. The patient died 16 days after admission. The pathology report showed massive hepatic necrosis and terminal shock.