Synthesis and antimycobacterial activity of some indole derivatives of pyridine-2-carboxamidrazone and quinoline-2-carboxamidrazone

M G Mamolo; L Vio; E Banfi

Synthesis and antimycobacterial activity of some indole derivatives of pyridine-2-carboxamidrazone and quinoline-2-carboxamidrazone

Farmaco. 1996 Jan;51(1):65-70.

Authors

M G Mamolo¹, L Vio, E Banfi

Affiliation

¹ Dipartimento di Scienze Farmaceutiche, Università di Trieste, Italy.

PMID: 8721764

Abstract

A series of pyridine-2-carboxamidrazone and quinoline-2-carboxamidrazone derivatives containing the indole moiety was prepared. Some of the synthesized compounds showed an interesting in vitro antimycobacterial activity against a strain of Mycobacterium tuberculosis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antitubercular Agents / chemical synthesis*
Antitubercular Agents / pharmacology
Microbial Sensitivity Tests
Mycobacterium tuberculosis / drug effects*

Substances

Antitubercular Agents