Role of nutrient density played in the genesis of stomach cancer was analyzed with a pair-matched case-control design to explore further the association between dietary nutrient and incidence of stomach cancer. Investigation of 88 pairs of cases with stomach cancer and controls showed high nutrient density of dietary vitamins C and A could protect from stomach cancer with OR of 0.34 and 0.46, respectively, and high of carbohydrate could increase risk of it with an OR of 2.20. Some problems in the use of nutrient density were discussed in the paper.