Bed rest decreases whole-body protein turnover in post-absorptive man

Clin Sci (Lond). 1996 Jan;90(1):73-5. doi: 10.1042/cs0900073.

Abstract

1. Whole-body protein turnover was measured using the [15N]glycine tracer technique in 10 post-absorptive healthy volunteers during normal daily activities and a period of bed rest. 2. Bed rest reduced whole-body protein turnover (25%), synthesis (26%) and breakdown (25%), but short-term urinary nitrogen excretion remained unchanged.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Absorption
  • Adult
  • Ammonia / analysis
  • Bed Rest*
  • Female
  • Humans
  • Male
  • Nitrogen Radioisotopes / pharmacokinetics
  • Proteins / metabolism*
  • Radioactive Tracers
  • Urea / analysis

Substances

  • Nitrogen Radioisotopes
  • Proteins
  • Radioactive Tracers
  • Ammonia
  • Urea