Abstract
Bioassay-guided fractionation of the MeOH extract of Ornithogalum saundersiae bulbs led to the isolation of a new cholestane bisdesmoside with potent cytotoxic activities toward leukemia HL-60 and MOLT-4 cells. The structure was deduced mainly from spectroscopic information.
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Antineoplastic Agents, Phytogenic / isolation & purification*
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Antineoplastic Agents, Phytogenic / pharmacology
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Carbohydrate Conformation
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Carbohydrate Sequence
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Cholestanes / chemistry
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Cholestanes / isolation & purification*
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Cholestanes / pharmacology
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Drug Screening Assays, Antitumor
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Gallic Acid / analogs & derivatives
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Gallic Acid / chemistry
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HL-60 Cells
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Humans
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Magnetic Resonance Spectroscopy
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Molecular Sequence Data
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Plants / chemistry
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Tumor Cells, Cultured
Substances
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Antineoplastic Agents, Phytogenic
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Cholestanes
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Gallic Acid
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3,4,5-trimethoxybenzoic acid