[Hard metal lung with diffuse small nodular shadows]

Nihon Kyobu Shikkan Gakkai Zasshi. 1996 Apr;34(4):465-70.
[Article in Japanese]

Abstract

A 32-year-old woman was admitted to Niigata University Hospital with dyspnea and a non-productive cough. She had been exposed to hard metal dust for 4 years in a metal-polishing factory. Chest X-ray and CT films showed diffuse small nodular shadows in both lung fields and pulmonary-function tests revealed severe restrictive impairment. Specimens obtained by thoracoscopic lung biopsy showed fibrosis in the centers of lobules and in peribronchiolar regions. Giant-cell interstitial pneumonia-like findings were also noted. Tungsten carbide and cobalt were detected in these specimens, with an X-ray microanalyzer. Hard metal lung was diagnosed. By 1 year after she changed her place of work and began corticosteroid treatment her symptoms and pulmonary function had improved remarkably, although shadows on chest X-ray films remained to some extent.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Cobalt / adverse effects*
  • Female
  • Humans
  • Lung / diagnostic imaging*
  • Lung Diseases, Interstitial / diagnostic imaging*
  • Lung Diseases, Interstitial / etiology
  • Pneumoconiosis / diagnostic imaging*
  • Pneumoconiosis / etiology
  • Radiography, Thoracic
  • Tomography, X-Ray Computed
  • Tungsten Compounds / adverse effects*

Substances

  • Tungsten Compounds
  • tungsten carbide
  • Cobalt