Increased light intensity prevents the age related loss of vasopressin-expressing neurons in the rat suprachiasmatic nucleus

Brain Res. 1995 Sep 25;693(1-2):261-6. doi: 10.1016/0006-8993(95)00933-h.

Abstract

We investigated whether increased light input can counteract the age-related decrease in vasopressin- (AVP) and vasoactive intestinal polypeptide (VIP)-expressing neurons of the suprachiasmatic nucleus (SCN) by determining the numbers of these neurons in rats of different ages, housed under low or high intensities of light. The significant age-related decrease for AVP was prevented in old animals after high light housing. For VIP, no effects were found.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging / physiology*
  • Animals
  • Cell Count
  • Immunohistochemistry
  • Light*
  • Male
  • Neuronal Plasticity / physiology
  • Neurons / chemistry*
  • Neurons / cytology
  • Rats
  • Rats, Inbred BN
  • Suprachiasmatic Nucleus / cytology*
  • Vasopressins / analysis*

Substances

  • Vasopressins