Abstract
Bovine herpesvirus 1 (BHV-1) is able to inhibit the proliferation of bovine peripheral blood mononuclear cells. Here, we have demonstrated that live BHV-1 and, interestingly, inactivated BHV-1 can induce apoptosis of mitogen-stimulated bovine peripheral blood mononuclear cells in vitro.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Apoptosis*
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Cattle
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Cells, Cultured
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DNA / metabolism
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Herpesvirus 1, Bovine / physiology*
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Ionomycin / pharmacology
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Leukocytes, Mononuclear / pathology*
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Phorbol 12,13-Dibutyrate / pharmacology
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Viral Proteins / analysis
Substances
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Viral Proteins
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Phorbol 12,13-Dibutyrate
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Ionomycin
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DNA