[Levels of interleukin-2 )IL-2 and tumor necrosis factor alpha (TNF-alpha) mRNA in aged rat spleen under physiological conditions and in septic shock: possible role of pidotimod in gene expression modulation]

Drugs Exp Clin Res. 1993:19 Suppl:9-14.
[Article in Italian]
No abstract available

MeSH terms

  • Adjuvants, Immunologic / pharmacology*
  • Aging / genetics
  • Aging / immunology*
  • Aging / metabolism
  • Animals
  • Escherichia coli Infections / immunology*
  • Escherichia coli Infections / metabolism
  • Gene Expression Regulation / drug effects*
  • Interleukin-2 / biosynthesis*
  • Interleukin-2 / genetics
  • Male
  • Pyrrolidonecarboxylic Acid / analogs & derivatives*
  • Pyrrolidonecarboxylic Acid / pharmacology
  • RNA, Messenger / biosynthesis*
  • Rats
  • Rats, Sprague-Dawley
  • Shock, Septic / immunology*
  • Shock, Septic / metabolism
  • Spleen / chemistry*
  • Spleen / drug effects
  • Spleen / pathology
  • Stimulation, Chemical
  • Thiazoles / pharmacology*
  • Thiazolidines
  • Tumor Necrosis Factor-alpha / biosynthesis*
  • Tumor Necrosis Factor-alpha / genetics

Substances

  • Adjuvants, Immunologic
  • Interleukin-2
  • RNA, Messenger
  • Thiazoles
  • Thiazolidines
  • Tumor Necrosis Factor-alpha
  • pidotimod
  • Pyrrolidonecarboxylic Acid