Abstract
The clinical cytogenetic findings of a patient with acute monocytic leukemia with peripheral and bone marrow basophilia are presented. The cytogenetic analysis of bone marrow cells established a pathologic clone with the following unusual karyotype: 47,XY,+X,t(2;10)(q21.1;q26.1). This chromosome abnormality has not been reported previously in leukemic diseases.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Basophils / pathology*
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Chromosomes, Human, Pair 10
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Chromosomes, Human, Pair 2
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Humans
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Karyotyping
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Leukemia, Monocytic, Acute / drug therapy
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Leukemia, Monocytic, Acute / genetics*
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Leukemia, Monocytic, Acute / pathology*
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Male
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Middle Aged
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Sex Chromosome Aberrations*
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Translocation, Genetic*
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X Chromosome*