Case of acute monocytic leukemia with 47,XY,+X,t(2;10)(q21.1;q26.1) and basophilia

Cancer Genet Cytogenet. 1996 Jan;86(1):80-2. doi: 10.1016/0165-4608(95)00056-9.

Abstract

The clinical cytogenetic findings of a patient with acute monocytic leukemia with peripheral and bone marrow basophilia are presented. The cytogenetic analysis of bone marrow cells established a pathologic clone with the following unusual karyotype: 47,XY,+X,t(2;10)(q21.1;q26.1). This chromosome abnormality has not been reported previously in leukemic diseases.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Basophils / pathology*
  • Chromosomes, Human, Pair 10
  • Chromosomes, Human, Pair 2
  • Humans
  • Karyotyping
  • Leukemia, Monocytic, Acute / drug therapy
  • Leukemia, Monocytic, Acute / genetics*
  • Leukemia, Monocytic, Acute / pathology*
  • Male
  • Middle Aged
  • Sex Chromosome Aberrations*
  • Translocation, Genetic*
  • X Chromosome*