Intracardiac thrombus may develop as a consequence of multiple underlying cardiac disorders. Other systemic disorders may predispose formation of thrombus within the heart, or the heart may be the site of emboli in transit--thrombus originating elsewhere and traveling through the heart to the pulmonary or arterial circulation. Part V of this five-part series on intracardiac thrombus will focus on "migrating thrombi," miscellaneous systemic conditions associated with intracardiac thrombi, and echocardiographic detection of intracardiac thrombus.