PCR-SSCP-HDX analysis of pooled DNA for more rapid detection of germline mutations in large genes. The BRCA1 example

Nucleic Acids Res. 1996 Mar 15;24(6):1177-8. doi: 10.1093/nar/24.6.1177.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • BRCA1 Protein
  • Base Sequence
  • DNA Mutational Analysis / methods*
  • DNA Primers / genetics
  • Female
  • Germ-Line Mutation*
  • Humans
  • Molecular Sequence Data
  • Neoplasm Proteins / genetics*
  • Nucleic Acid Heteroduplexes / genetics
  • Oncogenes*
  • Polymerase Chain Reaction / methods
  • Polymorphism, Single-Stranded Conformational
  • Transcription Factors / genetics*

Substances

  • BRCA1 Protein
  • DNA Primers
  • Neoplasm Proteins
  • Nucleic Acid Heteroduplexes
  • Transcription Factors