Celahinine A, a new sesquiterpene pyridine alkaloid from Celastrus hindsii

J Nat Prod. 1995 Nov;58(11):1735-8. doi: 10.1021/np50125a015.

Abstract

A new sesquiterpene pyridine alkaloid, celahinine A [1], and the related known polyester celahin A, as well as the known cytotoxic sesquiterpene pyridine alkaloid emarginatine A [2], were isolated from Celastrus hindsii. The structure of 1 was determined by 2D nmr techniques and was also confirmed by spectral comparison with the related 2.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents, Phytogenic / chemistry
  • Antineoplastic Agents, Phytogenic / isolation & purification*
  • Antineoplastic Agents, Phytogenic / pharmacology
  • Drug Screening Assays, Antitumor
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / isolation & purification*
  • Drugs, Chinese Herbal / pharmacology
  • Humans
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Pyridines / chemistry
  • Pyridines / isolation & purification*
  • Pyridines / pharmacology
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes / pharmacology
  • Spectrophotometry, Infrared
  • Tumor Cells, Cultured

Substances

  • Antineoplastic Agents, Phytogenic
  • Drugs, Chinese Herbal
  • Pyridines
  • Sesquiterpenes
  • celahinine A