Abstract
Tricycloillicinone (1), a novel tricyclic prenylated C6-C3 compound, has been isolated as a neurotrophic substance from the woods of Illicium tashiroi and its structure has been elucidated by spectroscopic analyses. Compound 1 could increase ChAT activity in culture of P10 rat septal neurons.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Brain / cytology
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Brain / enzymology
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Cells, Cultured
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Choline O-Acetyltransferase / metabolism*
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Dioxoles / isolation & purification*
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Dioxoles / pharmacology
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Models, Molecular
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Neurons / drug effects
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Neurons / enzymology*
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Plant Extracts / analysis
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Plants, Medicinal / chemistry*
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Rats
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Stimulation, Chemical
Substances
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Dioxoles
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Plant Extracts
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tricycloillicinone
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Choline O-Acetyltransferase