Cholesterol granuloma in the middle cranial fossa: report of two cases

Neuroradiology. 1995 Oct;37(7):564-7. doi: 10.1007/BF00593723.

Abstract

We report two cases of cholesterol granuloma in the middle cranial fossa. On CT the lesions appeared as a nonspecific, nonenhancing soft-tissue mass with bone erosion. On MRI they were seen as areas of high signal intensity surrounded by a low-intensity peripheral zone on both T1- and T2-weighted images. Cholesterol granuloma is thought to occur when pneumatised cells in the temporal bone become obstructed. Although this lesion usually occurs in the petrous bone, it can extend to the middle cranial fossa. The diagnosis and surgical management are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / diagnosis*
  • Brain Diseases / pathology
  • Brain Diseases / surgery
  • Cholesterol*
  • Diagnosis, Differential
  • Ear Diseases / diagnosis*
  • Ear Diseases / pathology
  • Ear Diseases / surgery
  • Ear, Middle* / pathology
  • Ear, Middle* / surgery
  • Female
  • Granuloma, Foreign-Body / diagnosis*
  • Granuloma, Foreign-Body / pathology
  • Granuloma, Foreign-Body / surgery
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Mastoid* / pathology
  • Mastoid* / surgery
  • Middle Aged
  • Petrous Bone / pathology
  • Petrous Bone / surgery
  • Temporal Bone / pathology
  • Temporal Bone / surgery
  • Tomography, X-Ray Computed*

Substances

  • Cholesterol