Influence of damage to the suprachiasmatic nuclei of the hypothalamus of rats on the dynamics of short-period fluctuations of normal and abnormal behavior

Neurosci Behav Physiol. 1995 Jul-Aug;25(4):290-5. doi: 10.1007/BF02360039.

Abstract

An intensification of a swimming behavior with an increase in the proportion of active swimming and limitation of the duration of immobilization was found in rats following bilateral electrolytic destruction of the suprachiasmatic nuclei of the hypothalamus. The restructuring of the temporal dynamics of swimming is manifested in a limitation of the rhythmological index of depressivity. The animals with ablated nuclei demonstrate more pronounced behavioral disturbances in response to the introduction of fenamin and a slowing of the minute fluctuations in the dynamics of stereotypic behavior.

MeSH terms

  • Amphetamine / pharmacology
  • Animals
  • Behavior, Animal / drug effects
  • Behavior, Animal / physiology*
  • Central Nervous System Stimulants / pharmacology
  • Male
  • Motor Activity / physiology
  • Paraventricular Hypothalamic Nucleus / drug effects
  • Paraventricular Hypothalamic Nucleus / physiology
  • Rats
  • Stereotyped Behavior / drug effects
  • Stereotyped Behavior / physiology
  • Suprachiasmatic Nucleus / anatomy & histology
  • Suprachiasmatic Nucleus / physiology*
  • Swimming
  • Time Factors

Substances

  • Central Nervous System Stimulants
  • Amphetamine