Chronic recurrent multifocal osteomyelitis is a rare entity with obscure etiology. A review of literature concerning clinical appearance, diagnostics and management of this condition is presented. Own material embraces a group of 7 children who have chronic recurrent multifocal osteomyelitis. Mean follow-up was 2.5 years. On the basis of results achieved the authors believe this condition is of good prognosis and should be differentiated with chronic osteomyelitis and neoplastic changes.