Ongoing vascular laboratory surveillance is essential to maximize long-term in situ saphenous vein bypass patency

J Vasc Surg. 1996 Jan;23(1):18-26, discussion 26-7. doi: 10.1016/s0741-5214(05)80031-x.

Abstract

Purpose: The purpose of this study was to assess the contribution of ongoing graft surveillance to maximize long-term patency of lower limb in situ saphenous vein bypasses.

Methods: From January 1981 to October 1994, 556 autogenous grafts were constructed in 499 patients. The distal anastomosis was at the popliteal level in 207 (37%) and the tibial level in 349 (63%). All patients were enrolled in a prospective surveillance protocol to identify lesions that compromise graft patency and were evaluated at 1 day, 1 week, 6 weeks, and 3 months. Surveillance studies were then obtained every 3 months for the first 2 postoperative years and every 6 months thereafter.

Results: Four-hundred-fifty abnormalities were detected in 236 grafts. The median interval from the initial procedure to detection of an abnormality was 12 months (range 0 to 113 months) and varied with the location of the defect. Later in the life of the graft, progression of atherosclerotic disease manifested as inflow obstruction at a median of 15 months, and outflow disease threatened the graft at a median of 29 months (r = 0.0003). Of the 450 surveillance abnormalities, 294 (65%) occurred within the first 2 years after operation, and 156 (35%) developed more than 2 years after operation. Of the 236 grafts that developed surveillance abnormalities, 50 (21%) developed the initial defect more than 2 years after the initial bypass procedure. Eleven percent of grafts remaining free of abnormality after 2 years went on to fail. Sixty-seven interventions were performed on 62 extremities after 24 months, with 30 involving previously unrevised grafts.

Conclusions: Because lesions amenable to revision continue to develop years after vein bypass construction, perpetual surveillance is required to ensure optimal rates of graft patency.

Publication types

  • Comparative Study

MeSH terms

  • Analysis of Variance
  • Female
  • Follow-Up Studies
  • Graft Occlusion, Vascular / diagnosis*
  • Graft Occlusion, Vascular / mortality
  • Graft Occlusion, Vascular / physiopathology
  • Hemodynamics
  • Humans
  • Life Tables
  • Male
  • Monitoring, Physiologic / methods
  • Monitoring, Physiologic / statistics & numerical data
  • Prospective Studies
  • Saphenous Vein / physiology
  • Saphenous Vein / transplantation*
  • Statistics, Nonparametric
  • Survival Rate
  • Time Factors
  • Transplantation, Autologous