Transcatheter arterial chemoembolization (TACE) in the treatment of unresectable liver cancer

World J Surg. 1995 Nov-Dec;19(6):795-800. doi: 10.1007/BF00299773.

Abstract

Basis, techniques, and recent strategies and results of interventional treatments for hepatoma were reviewed. The basic experimental researches indispensable to justify clinical technique and dosage have been accomplished. A total of 1310 unresectable cases underwent transcatheter arterial chemoembolization (TACE) and/or related therapies. The related therapies are several modified or strengthened TACE such as Lipiodol-TACE and subsegmental TACE. The therapies for unembolizable cases are balloon occluded arterial infusion, Lipiodol-SMANCS infusion and percutaneous direct injection chemotherapy, that reinforces the effect of TACE. As for the resectable cases, postoperative TACE was proved to be beneficial because it increased survival rates; however, preoperative TACE was not beneficial. The TACE and related interventional radiologic therapies for the hepatoma can be an equal or superior therapy by virtue of targeting chemotherapy.

MeSH terms

  • Chemoembolization, Therapeutic* / methods
  • Follow-Up Studies
  • Hepatic Artery
  • Humans
  • Liver Neoplasms / mortality
  • Liver Neoplasms / therapy*
  • Prognosis
  • Survival Rate