Activation of area V5 by visual perception of motion demonstrated with echoplanar MR imaging

R J Howard; E Bullmore; M Brammer; S C Williams; J Mellers; P Woodruff; A David; C Andrew; M Allin; A Simmons

doi:10.1016/0730-725x(95)00042-f

Activation of area V5 by visual perception of motion demonstrated with echoplanar MR imaging

Magn Reson Imaging. 1995;13(6):907-9. doi: 10.1016/0730-725x(95)00042-f.

Authors

R J Howard¹, E Bullmore, M Brammer, S C Williams, J Mellers, P Woodruff, A David, C Andrew, M Allin, A Simmons, et al.

Affiliation

¹ Institute of Psychiatry, Camberwell, London, England.

PMID: 8544664
DOI: 10.1016/0730-725x(95)00042-f

Abstract

Cortical activation in visual association areas known to be responsible for the perception of motion was investigated in two volunteers who viewed a projected animated cartoon periodically "run" and "frozen" during collection of echoplanar MR images. Ten axial, contiguous, 5 mm thick, T2-weighted, gradient-echo images (TE 40 ms, TR 3000 ms) depicting BOLD contrast were acquired through the occipital lobe using a GE Signa 1.5 T system with an advanced NMR operating console. Images were analysed by time series regression modelling estimating power in the MR signal at the ON-OFF frequency of motion. Highly significant activation in response to motion perception was identified in both subjects bilaterally in area V5.

MeSH terms

Echo-Planar Imaging*
Humans
Motion Perception*
Visual Cortex / physiology*