Natural killer cells. Right-side-up and up-side-down NK-cell receptors

Curr Biol. 1995 Sep 1;5(9):982-5. doi: 10.1016/s0960-9822(95)00194-1.

Abstract

Recent cDNA cloning of the receptors on human natural killer cells for MHC class I molecules reveals that human and mouse receptors have inverted structural orientations. Are there two distinct receptor systems?

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Humans
  • Killer Cells, Natural / immunology*
  • Mice
  • Receptors, Antigen, T-Cell / chemistry
  • Receptors, Antigen, T-Cell / genetics
  • Receptors, Antigen, T-Cell / immunology*
  • Receptors, Immunologic / chemistry
  • Receptors, Immunologic / genetics
  • Receptors, Immunologic / immunology*
  • T-Lymphocytes, Cytotoxic / immunology*

Substances

  • Receptors, Antigen, T-Cell
  • Receptors, Immunologic