Bronchial carcinoid associated with Cushing's syndrome

J Cardiovasc Surg (Torino). 1995 Oct;36(5):511-4.

Abstract

Bronchial carcinoid is the most frequent cause of Cushing's syndrome due to ectopic ACTH production. The authors report a case of bronchial carcinoid which diagnosis was difficult because of the presence of pulmonary mycosis, that determined a hypercorticosuprarenalism. Medical treatment with octreotide, ketoconazolo and mitotane was useless, and bilateral suprarenalectomy was performed. A scintigraphy with raced somatostatin revealed a left lung area capting radiation. A CT scan of the thorax revealed a lesion of the lingula and the patient underwent an atypical lung resection with complete solution of the symptom. The problems of diagnosis and treatment of neuroendocrine tumors of the lung are discussed and the importance of SSA in the diagnostic procedure is pointed out.

Publication types

  • Case Reports

MeSH terms

  • ACTH Syndrome, Ectopic
  • Adrenocorticotropic Hormone / metabolism
  • Adult
  • Bronchial Neoplasms / complications*
  • Bronchial Neoplasms / diagnosis
  • Bronchial Neoplasms / metabolism
  • Bronchial Neoplasms / therapy
  • Carcinoid Tumor / complications*
  • Carcinoid Tumor / diagnosis
  • Carcinoid Tumor / metabolism
  • Carcinoid Tumor / therapy
  • Cushing Syndrome / diagnosis
  • Cushing Syndrome / etiology*
  • Hormones, Ectopic / metabolism
  • Humans
  • Hydrocortisone / metabolism
  • Lung Diseases, Fungal / complications
  • Lung Diseases, Fungal / diagnosis
  • Male

Substances

  • Hormones, Ectopic
  • Adrenocorticotropic Hormone
  • Hydrocortisone