Immunohistochemical localization of cathepsins B and D in the synovial lining cells of the normal rat temporomandibular joint

Arch Oral Biol. 1993 Apr;38(4):357-9. doi: 10.1016/0003-9969(93)90144-b.

Abstract

In 1 micron-thick serial cryosections, cathepsins B and D were found to coexist in both type A (macrophage-like) and type B (fibroblast-like) cells: the whole cytoplasm of the type A cells showed strong immunoreactivity, while the type B cells contained a few granular reaction products. It is therefore suggested that type A cells have a marked ability for intracellular digestion of organic materials.

MeSH terms

  • Animals
  • Cathepsin B / analysis*
  • Cathepsin D / analysis*
  • Immunoenzyme Techniques
  • Immunohistochemistry
  • Male
  • Rats
  • Rats, Wistar
  • Synovial Membrane / enzymology*
  • Temporomandibular Joint / enzymology*

Substances

  • Cathepsin B
  • Cathepsin D