Chemical structure of the core region of Campylobacter jejuni serotype O:2 lipopolysaccharide

Eur J Biochem. 1993 May 1;213(3):1029-37. doi: 10.1111/j.1432-1033.1993.tb17850.x.

Abstract

The complete structure for the core region of Campylobacter jejuni serotype O:2 lipopolysaccharide (LPS) was assigned through studies on derivatives of the liberated oligosaccharide (OS 2) and the intact LPS. Structure determinations were performed using 1H-NMR spectroscopy, methylation studies supported by fast-atom-bombardment mass spectrometry and linkage analysis by gas chromatography/mass spectrometry, Smith degradation, and oxidation with chromium trioxide. It was concluded that complete oligosaccharide chains had the following structure: [formula: see text]

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Campylobacter jejuni / chemistry*
  • Carbohydrate Conformation
  • Carbohydrate Sequence
  • Lipopolysaccharides / chemistry*
  • Molecular Sequence Data
  • Oligosaccharides / analysis
  • Oligosaccharides / chemistry

Substances

  • Lipopolysaccharides
  • Oligosaccharides