Hepatitis viral markers in patients undergoing primary liver transplants

Dig Dis Sci. 1993 Mar;38(3):457-61. doi: 10.1007/BF01316499.

Abstract

The purpose of the study was to determine the prevalence in liver transplant (OLTx) patients of the hepatitis markers (anti-A, anti-B, anti-C, anti-D and HBsAg) and the interrelationships between markers and patients' sexes, ages, dates of transplant, clinicopathological diagnoses, and short-term survivals. Slightly more than half of the patients were male. Anti-A and anti-B were about evenly distributed between male and female. Anti-C, anti-D, and HBsAg were far more common in males. Age and year of transplant showed only a moderate increase in anti-A with increasing age. Anti-A was found in 57% of all patients, anti-B in 18%, anti-C in 17%, and HBsAg in 17%. Anti-D was tested only in patients who were positive for anti-B or HBsAg and occurred in 21 (11%) of 185. The poorest short-term survival occurred in males who showed both anti-A and HBsAg.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Female
  • Hepatitis Antibodies / analysis*
  • Hepatitis B Surface Antigens / analysis*
  • Hepatitis, Viral, Human / diagnosis
  • Hepatitis, Viral, Human / epidemiology*
  • Humans
  • Liver Transplantation* / mortality
  • Male
  • Middle Aged
  • Prevalence
  • Sex Factors
  • Survival Analysis
  • Time Factors

Substances

  • Hepatitis Antibodies
  • Hepatitis B Surface Antigens