[Expression of the Oct-2 protein during cell differentiation in vivo and in vitro]

Mol Biol (Mosk). 1993 Jul-Aug;27(4):817-26.
[Article in Russian]

Abstract

The expression of an Oct-binding protein Oct-2 was studied during differentiation of three cell lines. Two inductors were used in our experiments: retinoic acid and DMSO. It was shown that all these cells have heterogeneous population of Oct-2 mRNA. Under differentiation the pattern of Oct-2 RNA and expression of active Oct-2 proteins was changed.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Blotting, Northern
  • Cell Differentiation / drug effects
  • Cell Differentiation / genetics
  • DNA-Binding Proteins / genetics*
  • Dimethyl Sulfoxide / pharmacology
  • Embryonic and Fetal Development / genetics
  • Mice
  • Octamer Transcription Factor-2
  • RNA, Messenger / metabolism
  • Transcription Factors*
  • Tretinoin / pharmacology
  • Tumor Cells, Cultured

Substances

  • DNA-Binding Proteins
  • Octamer Transcription Factor-2
  • Pou2f2 protein, mouse
  • RNA, Messenger
  • Transcription Factors
  • Tretinoin
  • Dimethyl Sulfoxide