Abstract
The expression of an Oct-binding protein Oct-2 was studied during differentiation of three cell lines. Two inductors were used in our experiments: retinoic acid and DMSO. It was shown that all these cells have heterogeneous population of Oct-2 mRNA. Under differentiation the pattern of Oct-2 RNA and expression of active Oct-2 proteins was changed.
MeSH terms
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Animals
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Blotting, Northern
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Cell Differentiation / drug effects
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Cell Differentiation / genetics
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DNA-Binding Proteins / genetics*
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Dimethyl Sulfoxide / pharmacology
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Embryonic and Fetal Development / genetics
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Mice
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Octamer Transcription Factor-2
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RNA, Messenger / metabolism
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Transcription Factors*
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Tretinoin / pharmacology
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Tumor Cells, Cultured
Substances
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DNA-Binding Proteins
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Octamer Transcription Factor-2
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Pou2f2 protein, mouse
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RNA, Messenger
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Transcription Factors
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Tretinoin
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Dimethyl Sulfoxide