Abstract
The eye has traditionally been regarded as a sanctuary site for drugs, but recent publications have shown evidence of penetration by drugs and subsequent clinical response of intraocular lymphomas. In this report, a chemotherapy regimen, including high dose methotrexate and cytosine arabinoside, was used to re-induce remission in a patient with intraocular lymphoma relapsing locally after prior radiotherapy. She remains disease free 18 months later.
MeSH terms
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
-
Cyclophosphamide / administration & dosage
-
Cytarabine / administration & dosage
-
Doxorubicin / administration & dosage
-
Eye Neoplasms / drug therapy*
-
Eye Neoplasms / radiotherapy
-
Female
-
Humans
-
Lymphoma, Large B-Cell, Diffuse / drug therapy*
-
Lymphoma, Large B-Cell, Diffuse / radiotherapy
-
Methotrexate / administration & dosage
-
Middle Aged
-
Neoplasm Recurrence, Local / drug therapy*
-
Prednisone / administration & dosage
-
Remission Induction
-
Salvage Therapy
-
Vincristine / administration & dosage
Substances
-
Cytarabine
-
Vincristine
-
Doxorubicin
-
Cyclophosphamide
-
Prednisone
-
Methotrexate