Abstract
3-Hydroxy-4-methoxy-acetophenone (HMA) isolated from Cynanchum paniculatum was found to have analgesic effect and inhibitory action on the gastro-intestinal motility. The effect and action were equivalent to that of paeonol, HMA displayed a very low degree of antibacterial activity against Escherichia coli and Shigella flexneri.
MeSH terms
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Acetophenones / isolation & purification
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Acetophenones / pharmacology*
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Analgesics / pharmacology*
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Animals
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Drugs, Chinese Herbal / chemistry*
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Escherichia coli / drug effects
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Female
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Gastrointestinal Motility / drug effects*
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Male
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Mice
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Pain Threshold / drug effects*
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Shigella flexneri / drug effects
Substances
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Acetophenones
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Analgesics
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Drugs, Chinese Herbal
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3-hydroxy-4-methoxyacetophenone
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paeonol