Amides and formamidines with antinociceptive activity (note I)

Farmaco. 1993 Sep;48(9):1279-89.

Abstract

Pursuing our investigations on N-aryl or N-cycloalkyl substituted amides and formamidines with antiinflammatory and/or analgesic activity, two set of cycloalkyl substituted amides and formamidines were prepared and tested for analgesic activity against a chemical stimulus. Some compounds, particularly the amides 7, 11, 17 and the formamidine 35 proved to be endowed with this activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemical synthesis*
  • Amides / pharmacology*
  • Amidines / chemical synthesis*
  • Amidines / pharmacology*
  • Analgesics / chemical synthesis*
  • Analgesics / pharmacology*
  • Animals
  • Male
  • Mice

Substances

  • Amides
  • Amidines
  • Analgesics
  • formamidine