The clinical and pathologic findings of two cases of adenomyoepithelioma of the breast are reported. Aspiration cytology was performed in one case and was interpreted as malignant. Conversely, histological features revealed their typical architectural arrangement and immunohistochemical profiles confirmed that myoepithelial (actin and S-100 protein +) and epithelial (keratin and epithelial membrane antigen +) cells were active components in both tumours.