Histamine as an intracellular messenger in human platelets

J M Gerrard; S P Saxena; A McNicol

doi:10.1007/978-1-4615-2994-1_16

Histamine as an intracellular messenger in human platelets

Adv Exp Med Biol. 1993:344:209-19. doi: 10.1007/978-1-4615-2994-1_16.

Authors

J M Gerrard¹, S P Saxena, A McNicol

Affiliation

¹ Manitoba Institute of Cell Biology, Department of Pediatrics, University of Manitoba, Winnipeg, Canada.

PMID: 8209789
DOI: 10.1007/978-1-4615-2994-1_16

Abstract

The results of investigations in platelets provide evidence for an intracellular messenger role for histamine. Studies of neutrophils and of cellular proliferation suggest that there may be a wider role for histamine as an intracellular messenger modulating activation processes in cells.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Blood Platelets / physiology*
Cell Division
Enzyme Activation
Hematologic Diseases / physiopathology
Histamine / biosynthesis
Histamine / pharmacology
Histamine / physiology*
Histamine Antagonists / pharmacology
Histidine Decarboxylase / physiology
Humans
Intracellular Fluid / physiology
Neutrophils / physiology
Platelet Activation / drug effects
Polyamines / metabolism
Second Messenger Systems / physiology*

Substances

Histamine Antagonists
Polyamines
Histamine
Histidine Decarboxylase